Last week’s round-up, 02-06 December 2019

By Stephanie Allampalli and Marthese Mifsud   Metformin is being evaluated for nitrosamine impurity content. 06 December 2019 The Singaporean Health Sciences Authority has recalled some metformin products due to unacceptable levels of NDMA. On 5th December, the US FDA issued a statement saying that it has started evaluating metformin products for nitrosamines. (See link […]

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Last week’s round-up, 23-27 September 2019

By Tessa Fiorini-Cohen and Marthese Mifsud   EMA advises companies on steps to take to avoid nitrosamines in human medicines 27 Sep 2019 All EU marketing authorisation holders of medicinal products containing chemically synthesized APIs need to review their medicines for the possible presence of nitrosamines within the next six months. The EMA is sending a notice to […]

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Last week’s round-up, 02-06 September 2019

By Tessa Fiorini-Cohen and Marthese Mifsud   Has AI Discovered a Drug Now? Guess. 06 Sep 2019 The media is abuzz with reports that an artificial intelligence model has designed a drug in 21 days, however an opinion piece in Science Translational Medicine takes a more nuanced view. The software model is acronymed GENTRL (generative tensorial reinforcement learning), […]

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